CBD & Anxiety Relief without the High — Changing the Shape of Receptors
CBD can influence how a receptor transmits a signal by changing the shape of the receptor that is technically called “allosteric receptor modulation.” For example, CBD interacts with a receptor called GABA-A so that it enhances the receptor’s binding affinity for gamma-Aminobutyric acid (GABA). This is significant because GABA is the main inhibitory neurotransmitter in our nervous system, like the “CALM” dispensary product mentioned in an earlier blog, I like to think of GABA as the “volume down” button of the brain, quieting the noise of the mind. GABA is well-known in the medical world. We use prescription medications such as Valium, Xanax and other benzodiazepines to sedate and calm by mediating GABA receptor transmission.
When CBD is taken along with its sister cannabinoid THC, it changes the CB1 receptor so that it weakens its ability to bind with THC. The net effect is that CBD lowers the ceiling on the psychoactive properties of THC. The consumer can then have a therapeutic effect – allaying anxiety, for example – without the THC high and without the addiction threat of a prescription drug. Would you choose to take a non-addictive medicine to make you feel calmer while still being fully functional? Even a stoner would call that a no-brainer.
Meredith Patterson is a nurse specializing in neurology. She writes about the brain and brain health at her blog – www.BrainStormmindfitness.com.
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